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Title
2-D NMR Developments Improve Monoclonal Antibody Characterization
Monday, September 26, 2016
Kimberly L. Colson
Ten years ago, industry commentators noted the increasing importance of biologics, and monoclonal antibodies (mAbs), in particular.
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A Blood Separation Device That Eliminates Centrifugation and Reduces Preanalytical Errors and Turnaround Times
Friday, February 09, 2018
Darren Lee
Clinical diagnostic testing laboratories are under increased pressure to continually provide accurate results for each patient tested while reducing turnaround times (TATs).
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A Field-Portable Bioanalysis System
Tuesday, July 11, 2017
Varouj Amirkhanian
Eric Tsai
Alice Lin
A portable bioanalysis system provides high resolution and high detection sensitivity, and is a cost-effective solution for the field detection of pathogens.
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A New Era in Filtered Fume Enclosure Safety
Wednesday, June 07, 2017
The latest ductless filtered fume enclosures are a vital resource in the safe and effective operation of modern industrial, educational, hospital, forensic, and pharmaceutical scientific laboratories.
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A Portable CGE System for Cell Free DNA Detection
Monday, January 29, 2018
Varouj Amirkhanian
Eric Tsai
Alice Lin
Geoffrey Routh
A capillary gel electrophoresis system provides cost-effective cfDNA analysis for the noninvasive detection of cancer and prenatal genetic testing.
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A Redesigned Confocal Microscope for Super-Resolution Microscopy
Tuesday, May 09, 2017
Erik Manders
Peter Drent
Ronald Breedijk
A simple optical redesign converts a standard confocal microscope to a super-resolution microscope.
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A Review of Quetzal: A Linguistic Search Engine for Biomedical Literature
Wednesday, August 05, 2015
C. Tobin Magle
Quetzal is a biomedical literature search engine that uses simple strategies that contain few keywords combined with an extensive biomedical vocabulary and filter sets that mirror the discovery ...
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An Effective Treatment Strategy for Cytokine Storm in Severe Influenza
Tuesday, July 25, 2017
Erin Murphy
Despite the use of vaccines and antiviral therapies such as oseltamivir, severe influenza kills thousands to tens of thousands of Americans each year.
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Automated On-Line Extraction and Analysis of Dried Blood Spot Cards
Wednesday, January 16, 2013
Lester Taylor
Na Pi Parra
Doug McIntyre
The use of dried blood spot cards for screening neonates for metabolic and genetic disorders was conceived and proposed almost 50 years ago. Since then, newborns in many countries have had their ...
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Automating 3-D Cell Culture and Screening by Flow Cytometry and High-Content Imaging
Friday, November 04, 2016
Michael Kowalski
For over half a century, researchers have used 2-D cell culture methods, though the physiological relevance of these models has frequently been in doubt, largely because monolayer culture systems ...
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Best Practices for CO
2
Incubator Maintenance
Friday, July 22, 2016
Mary Kay Bates
The use of long-established mutant lines in culture has shifted, and it is common to find researchers using more sensitive stem cells, primary cells and 3-D cultures in applications including vaccine...
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Cell Culture Advances Yield More Reliable Data for Cancer Research
Tuesday, July 26, 2016
James Lim
Cells stored with traditional culturing practices express different gene and protein profiles than their in vivo counterparts.
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Centrifugation: Best Practices for Reliable, Reproducible Results
Wednesday, February 14, 2018
Hugh Tansey
Laboratories can benefit from advances in centrifuge functionality and performance, as well as ergonomics and ease-of-use.
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Comparative Analysis of Antinuclear Antibody and Antinuclear Antibody Spectrum
Friday, February 28, 2014
Cui Kong
Jianwei Zhou
Jinsong Sun
Aihua Shen
Qin Song
Xinke Chen
Li Li
The occurrence of autoimmune disease (AID) has increased 3–5% and has had a significant impact on human health. The detection of serum antinuclear antibody (ANA) is beginning to receive more attention...
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Delving Deeper Into the Proteome With Novel Mass Spectrometry Methods
Tuesday, August 07, 2018
Gary Kruppa
Scarlet Koch
The integration of a novel separation technique and application of a sophisticated scanning method has enabled researchers to dig even deeper into the proteome.
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Determination of Pain-Management Drugs in Human Urine Using “Flip-Flop” Chromatography and Time-of-Flight Mass Spectrometry
Monday, July 25, 2016
Ihuoma A. Igwilo
Nicholas T. Lappas
Ira S. Lurie
Methodology is presented for analysis of 13 pain-management drugs using reversed-phase and hydrophilic interaction chromatographic separations.
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Differential Response of Breast Cancer Cells Cultured in 2-D Versus 3-D to Estrogen Receptor-Targeting Therapeutics
Wednesday, August 07, 2019
Erin Edwards
Thomas S. Villani
Graeme Gardner
Michael T. Johnson
Elin Agoston
A comparison of 2-D and 3-D breast cancer cell culture models reveals that culture method affects estrogen receptor expression.
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DNA Modification in Obese Persons: Detection and Estimation of Carboxymethyl-2’- Deoxyadenosine in Human Urine and DNA
Monday, September 01, 2014
Zeenat Ara Lila
Dawnn Flowers
Morgan Tubman-Jackson
Genetics, obesity, and lack of exercise play a vital role in the development of diabetes. Almost 80% of people with Type 2 diabetes are overweight.
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High-Throughput Drug Screening of Multicellular Tumor Spheroids
Tuesday, September 27, 2016
Ana Maria P. Pardo
Hannah J. Gitschier
David H. Randle
Terry Riss
Three-dimensional (3-D) culture models are increasingly being used for drug discovery in oncology, as they better represent the complexity of the in vivo microenvironment of solid tumors.
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How Lab Informatics Technologies Help Meet Evolving Healthcare Needs
Wednesday, February 05, 2014
Shooki Grasiani
Don Koch
Randy Hice
As U.S. healthcare providers (HCPs) navigate a changing healthcare climate, diagnostic laboratories are playing an increasingly important role in helping them prevent medical errors, lower ...
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